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Morpholino Summary
General Information
Morpholino name: JR0001b    
Morpholino sequence: GTTTTTCAGTAACCCCTCCCATCAT
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Target name: Smoothelin
Target sequence: (Morpholino Target and ATG)
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GGAGAGCACCATTTATCTTCAAGTTTTCTTTCCTCGAGTGCACAAAAAGTCTGATAGCACTTTTGAAAGTGACAGTGTTTAGATTAAACGCTGACGCACTGTTATCTTGAGAGCAGAGACAGGAAAGGGAATGATCAGGACAAGCAGTGCCAAATAGTTTACTAATACTTAATGTCTCGTTCTAATAGAGACTTTTTTGTTTGTTTTGTTTCTGGTCCTTTCAGAAGTGGGTGATGATGGGAGGGGTTACTGAAAAACTCATTCAGTCCAGCATCAGAGCAGAGTATTATATGGTAAATCCCTCTGTTCACCTTTCTAGATCACACTGCAAGAGCTTTCCTCTCGGACGTCCGGACTGAGACTGCTGTCACTGAAGATGGAGGCTGAGAAGGGAACATTAGAGGCAGGTACCAAAGAGCAGGCCGATACCATGGGTCAACTGACAGCAGAACAGCTGGCCGCTATAGAGGATGAAGAGATCCTCAATAACATGAACGGCGTGATCGTGAGCGGGCGGCCCGCATGGAGAACCTGCGTCAGGGCACTGGAGGAAAGACATCTGCTAGCCTCAGTAAGGATCAGAAAGCCTCTAATGGTCCCGGCGGTGCTCAATTCAACGCACACAGAACAGCTCAGGCAAAAACACTTTCACAACCAACCTCAGTTTCCTCTCCGAAAACGATGAGCAGCCCGGCTCAGTCCCATGTGGCCAGGGTTAAAATGTCTGGCGGTTCTGCAGTCGGAGGCCCAAACACCAAAGATGTCAAACAGATGCTGCTGGACTGGTGCCGTGTGAAGACTGAGCCATATGAGGGTGTGAACATCCAGAATTTCTCCTCTAGCTGGGCTGACGGTCTGGCCTTTTGTGCACTGGTGCACAGGTTCTTTCCAGAGGGCTTTGAATATTGTACTCTTAACCCTTATGACCGCAAATCCAACTTTGAGAAGGCATTCAAGACTGCAGAGAGACTAGCCGACTGTCCTCCCCTGCTGGACGTTGATGACCTGATGCGGATGCGGGAACCCGACTGGAAGTGCGTTTACACGTATATCCAGGAGTTTTACCGCTGCCTAGTAGAAAAAGGCCTTGTCAAGACTAAAAAGAAGATGCCATAGAAACACAAAACTCCCACACTGTGAGTGTTTTCACTGACCAAGAGACTACAACAGGCACACAACACAGCATACATGTGACCTGAAGCTTTGCCAAAGACCAAAGAGTCTATTACATTCTTATGCTCGTCTCTGTTTCATATCAGCACATGCAGTGGATGAGGATTATAACCTGTATGTTTGGCACTAGGGTACAGCTGGGGCTCTGAAACTGCACATTCCAGCGAGATTACACATGCATTAATCTCAGTATGTGCTCAGAGATTGTGTGAATGTGTGTGTGTGTGCGCGCGAATGTCTTTTTATGGTACTGCTACTCCCCATTTTGAAAGTGCTCCAGCAGAGAGACATCAGGCTTATAAGGGCATGAGATCTAATGCTGAATTATACTTATCCCTGATTTATCGTTTGTTTAAAAATACTGGCGGGCACTTGTACTGTTATGTAAAGGAGTTCAGAAAAGAAAACAACGTTTTAAAAGGGCTACATTTAGAATTCAGAAGCATACGTTATTAGCGACGCCGGTGGCTCTTAAGTGAACTGCAGCTATATTTTTTTCATGAATAATTGCAGACTTGACATGATCCAATGCCTTCAACATTATGAAAATATGTACTGCTTACGATAATTAGGAAACCATTAATATATAGATGAATGAGCGCATAAACATTTTTTATATTCCTAAAATATATATATTTTACTTTTATTTATTTAAATTTTTCAAAAACATCCTGAGTCCTTTACACAAAATTGGTCTATTCTAAACACTTACTAAGACAACCTAGGAAGTAAGTCAGAATGTTAATTACAATCTATTTGAATATAACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Gene targeted:
not assigned
Synonyms:
Comments:
Reference:

Survival Curve: Normality Curve:
Note: When more than one data point existed per dose an average was used. p53 morpholino co-injections were used to minimize non-specific toxicity effects (Robu et al. PLoS Genetics 2007)
Screens Performed (number of tests): Defects Observed:
Morphology: (7)
Kidney: (2)
Pigment: (4)
Vasculature: (4)
Eye: (2)
- pigment cells colorless
(100%, dose:1.5ng, p53:2.25ng, days: -)
- tail coiled
(10%, dose:1.5ng, p53:2.25ng, days: -)
- pigment cells colorless
(100%, dose:3ng, p53:4.5ng, days: -)
- trunk coiled
(100%, dose:3ng, p53:4.5ng, days: -)
- tail coiled
(100%, dose:3ng, p53:4.5ng, days: -)
- head small size
(70%, dose:4.5ng, p53:6.75ng, days: -)
- trunk coiled
(80%, dose:4.5ng, p53:6.75ng, days: -)
- tail coiled
(80%, dose:4.5ng, p53:6.75ng, days: -)
- pigment cells colorless
(100%, dose:6ng, p53:9ng, days: -)
- notochord short length
(50%, dose:6ng, p53:9ng, days: -)
- somite square
(50%, dose:6ng, p53:9ng, days: -)
- head small size
(50%, dose:6ng, p53:9ng, days: -)
- trunk coiled
(50%, dose:6ng, p53:9ng, days: -)
- tail coiled
(35%, dose:6ng, p53:9ng, days: -)
- pigment cells colorless
(100%, dose:9ng, p53:13.5ng, days: -)
- tail coiled
(10%, dose:9ng, p53:13.5ng, days: -)

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