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Morpholino Summary
General Information
Morpholino name: HS2086    
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Target name: TTF1
Target sequence: (Morpholino Target and ATG)
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Gene targeted:
not assigned

Survival Curve: Normality Curve:
Note: When more than one data point existed per dose an average was used. p53 morpholino co-injections were used to minimize non-specific toxicity effects (Robu et al. PLoS Genetics 2007)
Screens Performed (number of tests): Defects Observed:
Blood: (1)
Vasculature: (7)
Kidney: (4)
Toxicity: (7)
Pigment: (10)
Eye: (5)
Morphology: (4)
- head [proposed pooling]
(28.57%, dose:1.5ng, p53:2.25ng, days: -)
- heart edematous
(14.29%, dose:3ng, p53:4.5ng, days: -)
- iridophores decreased number
(10%, dose:4.5ng, p53:6.75ng, days: -)
- head [proposed pooling]
(14.29%, dose:4.5ng, p53:6.75ng, days: -)
- eye small size
(10%, dose:6ng, p53:9ng, days: -)
- eye dysplastic
(10%, dose:9ng, p53:13.5ng, days: -)
- eye medial
(10%, dose:9ng, p53:13.5ng, days: -)
- cardiovascular system [propose decreased flow]
(14.29%, dose:12ng, p53:18ng, days: -)