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Morpholino Summary
General Information
Morpholino name: HS2081    
Morpholino sequence: TCTTGGAGCCCATTGAGACAGTACC
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Target name: pb1
Target sequence: (Morpholino Target and ATG)
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TTACAGAAGGATTATTCCTAACTGCGCCAATATCGTCGCGATAATACGGGTACTGTCTCAATGGGCTCC AAGAGAAGACGAGCCACCTCTCCCTCCAGCAGTGCCAGCGGAGGATGCACTTATGGAGGACATGAAGCTT ATGTTTCGTAATGCCCGCCACTATAATGAGGAGGGATCTCAGGTTTATAATGATGCAAATGTCTTGGAGA AGATGGTTAAGGATAAACAGAAGGAGCTTGGCCCTGCTCCAGAGGAAGATGACGTTGGCTCTCCCAAACT CAAGCTTCGCCGTAGTGGAGTTGCAGTCTCCCCTAAAAAGGCTCGCATCCAAACTACACCACTCCAGCAG AAGCTCAGCGAGCTCTACGAAGCTGTTCGCAACTTCACAGACAATCGTGGCCGTCGTCTCAGCACCGTTT TCCTGCGGCTGCCATCCCGTTCTGAACTGCCTGACTATTACGCTGCTATTAAGCGTCCAATCGACATGGA GCGAATACGCGGCTACATGGTGCAGGGACGCTACCAGGATGTTGATTCACTGGCAGAAGACTTCATCCTC ATGTTCAACAATGCTTGTACATACAATGAGCCAGAGTCTTTAATATATCGTGATGCTCTGTTGCTCCATC GAGCATTTCTGGAAGCTCGTAGACGGATTGAGGAAGAGGAGAATGGAGATGAAGGTGGTCTGGGGGGTTT GTCGGTTGCCTCTCTTGTGCGTGAGCTCATCCGAAACCTCTTTGTGTCAATGATGGGGCACCAGGATGAC GAAGGCCGATGCTATAGTGACTCTTTGGCGGAGGTGCCTGCAATCGACCCAGCTAACCCAGATGATCCAC CCCTTACTTTAGAGATCATTCGCAATAATGTGGATAGTGGCCGCTACCGGAGACTGGATGTCTTCCAGGA GCATGTGTTCGAGGTGCTGGAGAAAGCTAGACGTCTCAACAGGACTGATTCTGAGATCTTTGAGGATTCT GTGGAGCTGCAGCATTTCTTTGTGAAGATCCGTGATGAGCTGTGCAAAAATGGTGAAATCCTGCTGACCC CAGCACTGAGCTACACATCCAAACATCTGCATTCAGACATAGATCAAGAAAAGCGAGAGAAACTGCCCCA GGAAATTGAGGAAGACCAACTGAAACGGGAGGAGGATAAAAAAGCTCTTCCAGAAGGGGACAAAGCAGAG GGTCCTGCAGAAGGTGGCCAGTGGCCATCAGGTTCTCAAAGCTCTTATAGTCAGGACTGCAGTTTTGAAA ACAACACCTACAGCATAGGAGACTACGTATATGTTCAGCCCACAGTTAGCAAATGGGACCAGAGCCTTAA GGCACAGAGAAAAGACTGCCGGCTTAGTAGGGAACAGGAGAGTCATCTCCCTACTCACTGGCTGAAAAGC AAAGGCGCTCACACCACGATGGCCGATGCTTTATGGAGACTCCGAGACCTGATGATGAAAGACACGCTCA ACATCCGACAGGCGTACAACCTTTAAACCTTTACCTTTTACCCTAAACTCTCAGGACTGTAATTTATGCA AGACTTTTCTCCAACCAAATCTTTCCCATCATGACTCAAGATGTGATCAAGTGTTAATGTACTGTTGCAA AAGTGCTTCAGCAATAATTATATCTATCAGTTGTGTGTTTGTAAATGCGTGTGTGAAGAGAAAAATAAAC ATTTTCCCACCTCTTTTGATATATATATATAGAGCCCTGGAAAGAAGTCACACTTTTTTAATTCATAACT AACATGGATTTGATATTTGTCATTTGGACTGTTACCTCAATTAAGGTTGAGTTTATGAATACTACATCAC AAGTCTTCACGAAGTTTTACATCTATGACTATTCTAAAATGCTTAATATGAGTTGTTGAAGAACACAGTA GCATTTTATAAAGATGTTTTCTTTTTATACGGAGGTAAAACTACATGAGCTCCTACTTATTTTAATGATA ATGCAATTTGTTATTTTTACACTGTGTACATACAAAAAAATTGTGTGAACTGTTGCTTATTGAACACTGC TGCATTAAAAAAAAGACAAAACTGTGTCAATTACACCAATAAACGGCATTACAGATGGATAAAGTGCGCT TCAAGTGTGTCCAAAACATGTTTGTGAGAGGATTGAGTTTCAAGCCCCTCCACCCGCCACCACTGTAACA CAAGGCCCGCTTATTGACCACAAAATTTACCTCAGCAAATACAGTTTACCTTTAAATATGAGTTGTTAAA TATCAGAACTGCTCGAAAAAAAAAAAAAAAAAAAAAAAA
Gene targeted:
polybromo 1
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All the morpholinos targets to the gene
Synonyms:
Comments:
Reference:

Survival Curve: Normality Curve:
Note: When more than one data point existed per dose an average was used. p53 morpholino co-injections were used to minimize non-specific toxicity effects (Robu et al. PLoS Genetics 2007)
Screens Performed (number of tests): Defects Observed:
Pigment: (6)
Kidney: (1)
Toxicity: (2)
Eye: (2)
Vasculature: (4)
- heart straight angle
(14.29%, dose:3ng, p53:4.5ng, days: -)
- head [proposed pooling]
(14.29%, dose:3ng, p53:4.5ng, days: -)
- tail coiled
(14.29%, dose:3ng, p53:4.5ng, days: -)
- head dysplastic
(14.29%, dose:4.5ng, p53:6.75ng, days: -)

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