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Morpholino Summary
General Information
Morpholino name: HS2071    
Morpholino sequence: GATAGTCGTCCTACCTTCATAAAGC
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Target name: DLC1
Target sequence: (Morpholino Target and ATG)
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NKNOWN
Gene targeted:
not assigned
Synonyms:
Comments:
Reference:

Survival Curve: Normality Curve:
Note: When more than one data point existed per dose an average was used. p53 morpholino co-injections were used to minimize non-specific toxicity effects (Robu et al. PLoS Genetics 2007)
Screens Performed (number of tests): Defects Observed:
PAX2: (4)
Blood: (20)
Eye: (10)
- eye absent
(85.71%, dose:1.5ng, p53:ng, days: Day: 3)
- eye dysplastic
(85.71%, dose:1.5ng, p53:ng, days: Day: 3)
- eye small size
(85.71%, dose:1.5ng, p53:ng, days: Day: 3)
- blood decreased
(50%, dose:3ng, p53:ng, days: 48 hours)
- cardiovascular system [propose absent flow]
(60%, dose:3ng, p53:ng, days: 30 hours)
- cardiovascular system [propose decreased flow]
(60%, dose:3ng, p53:ng, days: 30 hours)
- eye absent
(100%, dose:3ng, p53:ng, days: Day: 3)
- eye dysplastic
(90%, dose:3ng, p53:ng, days: Day: 3)
- eye small size
(90%, dose:3ng, p53:ng, days: Day: 3)
- tail [proposed pooling]
(50%, dose:3ng, p53:ng, days: 48 hours)
- blood decreased
(90%, dose:6ng, p53:ng, days: 48 hours)
- cardiovascular system [propose decreased flow]
(90%, dose:6ng, p53:ng, days: 48 hours)
- intermediate cell mass of mesoderm large size
(90%, dose:6ng, p53:ng, days: 48 hours)
- eye absent
(71.43%, dose:6ng, p53:ng, days: Day: 3)
- eye dysplastic
(57.14%, dose:6ng, p53:ng, days: Day: 3)
- eye small size
(71.43%, dose:6ng, p53:ng, days: Day: 3)

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