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Morpholino Summary
General Information
Morpholino name: HSST2    
Morpholino sequence: 5'-AGTGAAAGCATTACTCGGTTGTGCG-3'
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Target name: hs6st2
Target sequence: (Morpholino Target and ATG)
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CACGCGTCCGGAAGAATCACAAAGCAATCCGATGTAAGTTCGGACTACAAAGCCTCGTGGAAACATGTA GACACCGACTAGACTCGCTTCAATCAAACGAACATCCACCAGAAGCGCTGGGCGTGTTCGTGTTTTGATG TGCTCGAGTCACAGGTTTTGTTCAACATTCCTCCTGGCCGACGCGACGCGGTGAGCGAGCCGCCGCACAA CCGAGTAATGCTTTCACTTTTCCAGCGAGAAGATGGATGGGAAATCCAACTACAGCCGGCTACTCATCGC GCTGCTGATGATTCTGTTTTTTGGCGGAATTGTACTGCAATACATATGTTCAACATCCGACTGGCAGTTA CTACACCTGGCATCATTGTCCTCGAGGCTGGGGAGTCGCGCGCCCGGAGATCGCTTGAACGGAGCCGGTG CGGGAGATCCGTACAGCTCGGAGGACGGTGCTTTGGTTCGCTTTGTGCCTCGTTTTAATTTTACCACTAA AGACCTTAGTCGCGCGGTGGATTTCCACATTAAGGGGGACGATGTTATTGTGTTCCTCCACATTCAAAAA ACCGGTGGGACCACATTCGGCCGTCACCTGGTCCGCAACATCCAGCTGGAGAGGCCGTGCGAGTGCCATG CGGGCCAGAAGAAGTGTACCTGCTACCGGCCGGGCAAACGCGACACCTGGCTGTTCTCCCGCTTCTCCAC CGGCTGGAGCTGCGGTCTGCACGCGGACTGGACCGAGCTCACCAACTGCGTGCCTTCCTTCATGAGCAAC CGGGAGTCCCAGGAGAGACGCATGACTCCTAGTAGGAACTACTACTACATCACCATCTTGAGGGATCCGG TGTGGCGGTATCTCAGCGAATGGAGGCACGTTCAGCGTGGAGCCACTTGGAAAGCTTCTAAACACATGTG TGACGGCCGTTTACCCACCCTGACCGAGCTGCCCAGCTGTTATCCTGGCGACGACTGGTCCGGCTGCTCG CTGGAGGAATTCATGGTGTGCCCTTACAACCTAGCCAACAACAGACAGACCCGAATGCTGGCCGACCTCA GCCTGGTGGGCTGCTATAACCTCACGGTAATGAGCGAGAACCAGCGGTGGGCCATGCTACTGGAAAGTGC CAAGCGCAACTTGCGAAACATGGCCTTTTTTGGTCTGACCGAATATCAACGTAAGACGCAGTACCTGTTT GAACACACGTTCCGTCTTTCCTTCATCGCACCTTTTACACAGCTTAACGGCACCCGTGCTGCGAGCGTAG AAGTGGAACCGGAGACCCAACGCAGAATTCGAGAGCTTAACCAATGGGACGTGGAGCTATATGAATATGC ACGGGATCTTTTCCTCCAGCGCTTCCAGTTCGCCAGACAGCAGGAGCGCAGGGAGGCCCGTCAGCGACGC ATACAGGAGCGGCGAAAGCTACGTGCCAAGGTGAAGTCTTGGTTGGGGGTGACTGGAAAAGCGGTTTTTA AACCCACCAAGGAGCCACCAATGACAGAGCAGTCGCCCGCTTTTGCTGAAGAAAAACAAGCAGATGCTGA ACAAACGCTGGAGAGCGAGACCGAAGGACAGGTAGAGGAGAACTGGCTAGAGGAGGATGACGGTGAAATC ATGTTGGACTATTCAGAAAACGTAGAGCAGTGGCGGTAGCATTTGGGAAGAGGGTTGAACTTAATACTGA ACTAGAAAATGGTGATTCCATTTGATTACTTTATGGTACCTATAATCCTCGAAGCCCAAATCACTGCTGA ATATTAGCAATATACGGGTTGTTTATTGTGGGTTGCTTTTTATGTCACGTGCATTTGGTGAAATGCACAT GGAAATCTTCATATGTATCAGTTATTGGCTCCAGTTCTCTGTCAGATATCAATGAATGATCATCTGCAGC CTGACTCATCTTGTGAACTGAAGAGATGGTAAAATCCACTGTCCCATCAGCACTTTGCCCTTGAGAGAGG GCATTGTGAATTGCCGGTTGCACCAGGGAGGTCGTCTCTGCAGTTCTTGTACTGAAAATCACAATGCTTA TTGTGAAAGCCAAAGAGTGGAATGTTTCAGAAATGAGGGGGGAGCCAGGGTGGCTGCACATTTGTATTTA CATTCCTGTAATGCAAGTTTTTAGTTATTGCCTAATCATTTTTCAAGTGTCTTCAACTTTCACAATCCCA TGCATATCACGTCAGCCTTATGTCAAAGTCCAACACTTGTCTTTGTGTTTTTTTATATACATATATCTAT AAATATGCATTTCCTTCTCATTCTTTTATTTATATGTTTGCTAATAAATCACAGGATTTGGGTTGGCTCT GATTTTTCATTACTTGAAAGTAAAAAGCCATTAAGTTACTATGTCTTTATGCCACACCATATGTGTACTG AGGAGCACTGATTGCTCTGCTCTGGAAAGAATGATTACATTTGTGAATAATAATAAATACATTTTATAAT AATCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAG
Gene targeted:
heparan sulfate 6-O-sulfotransferase 2
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All the morpholinos targets to the gene
Synonyms:
Comments:
Reference:

Survival Curve: Normality Curve:
Note: When more than one data point existed per dose an average was used. p53 morpholino co-injections were used to minimize non-specific toxicity effects (Robu et al. PLoS Genetics 2007)
Screens Performed (number of tests): Defects Observed:
None

Images


Figure 1. Disruption of tail redomeling in the GFP::Fli1 embryo and reduced circulation and blood pooling in the dsRed::Gata embryo.