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Morpholino Summary
General Information
Morpholino name: Lcathepsin M2    
Morpholino sequence: CCAGGAGGACTTTCACAAGCAAACC
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Target name: ctsl1b
Target sequence: (Morpholino Target and ATG)
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GTAAGGTTTGCTTGTGAAAGTCCTCCTGGCAGGATGATGTTTGCTTTGCTCGTCACGCTGTGCATAAGT GCAGTGTTTGCTGCTTCATCTATAGACATCCAGTTAGACGACCACTGGAACTCCTGGAAGAGCCAGCATG GAAAAAGCTATCATGAGGTGGGAAGACTGTAGTCTGTAGCCATGTATCAGCTTAACATGAATGAATGATA CAGTGCATGTGTTTATGTTGAACTGGTGCTTTGCAATAGCTGCTACAGTATCTACTTTCTACTCCAGGAC GTAGAGGTCGGGAGGAGAATGATTTGGGAGGAGAACTTGAGAAAAATTGAGCAACACAACTTTGAGTATT CCTATGGAAATCACACCTTTAAAATGGGAATGAATCAATTTGGTGACATGACAAATGAGGAGTTCAGACA GGCAATGAATGGTTATAAGCATGACCCCAACCGGACGTCACAGGGCCCGTTGTTCATGGAACCCAGCTTT TTTGCAGCCCCACAACAGGTTGACTGGAGACAGAGGGGCTATGTTACTCCTGTCAAAGACCAGAAACAAT GTGGATCTTGCTGGTCTTTTAGTTCAACGGGTGCCTTGGAAGGTCAGCTCTTCCGTAAAACTGGAAAGCT GATTTCTATGAGTGAGCAAAACTTGGTGGACTGTTCCAGACCACAGGGCAATCAAGGGTGTAATGGAGGC ATCATGGACCAGGCCTTCCAGTATGTTAAAGAAAACAAGGGGCTGGATTCTGAGCAGTCATACCCTTATC TTGCAAGGGATGATCTGCCATGCCGGTATGACCCCCGTTTTAATGTAGCTAAAATCACCGGATTCGTGGA CATCCCCAGAGGTAATGAGCTTGCTCTGATGAATGCTGTTGCTGCTGTGGGTCCTGTATCTGTTGCTATT GACGCATCACATCAATCCCTACAGTTCTATCAGTCTGGCATCTATTATGAGAGAGCATGTACCAGTCGAC TTGATCATGCAGTCTTGGTGGTTGGCTATGGTTATCAGGGTGCTGATGTTGCTGGGAATAGATACTGGAT TGTGAAGAACAGCTGGTCTGACAAATGGGGTGACAAAGGCTACATCTACATGGCAAAAGACAAAAACAAT CACTGTGGCATTGCGACAATGGCCAGCTATCCCCTAATGTAAGGCCACTGGAGCCTTCTCTGCATTCTGA AAAAGTCACGTTTATGGTTTCTCTATTTTAATGTTTTTATTTCTTCTATTTTATCAAGTTGTTCTGCTGT TAGCGCTATGATAGTAGTATTTTAGGAAATTCCATTTTTCTTGTGTTTCATATATTTTTGTTTATCCAAG AATTTTGTACTGGATCTATTTGACCTGCAAATGGATAAATATTAAATATTCTGGCATGGCA
Gene targeted:
cathepsin L, 1 b
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All the morpholinos targets to the gene
Synonyms:
catL, ctsl1b, cathepsin L, cb15, ctslb, hgg1, cts
Comments:
Reference:

Survival Curve: Normality Curve:
Note: When more than one data point existed per dose an average was used. p53 morpholino co-injections were used to minimize non-specific toxicity effects (Robu et al. PLoS Genetics 2007)
Screens Performed (number of tests): Defects Observed:
Eye: (4)
- eye absent
(20%, dose:3ng, p53:ng, days: Day: 2)
- eye absent
(40%, dose:6ng, p53:ng, days: Day: 2)
- eye absent
(40%, dose:6ng, p53:ng, days: Day: 3)

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