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Morpholino Summary
General Information
Morpholino name: LaminA b    
Morpholino sequence: 5'-AGAGAGTTTGGGTTAGTGAAGCTCC-3'
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Target name: lmna
Target sequence: (Morpholino Target and ATG)
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CAGCACACACTCTTTCAGCAGAGTTTACGCGGGGCACAGCAGCTGTAGGAGCTTCACTAACCCAAACTCTCTCTCTCAGCTTTACCAGTATCAGTAGTTCCAGACAACCATGGAGACTCCAGGTCAGAAA
Gene targeted:
lamin A
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All the morpholinos targets to the gene
Synonyms:
Comments:
Reference:

Survival Curve: Normality Curve:
Note: When more than one data point existed per dose an average was used. p53 morpholino co-injections were used to minimize non-specific toxicity effects (Robu et al. PLoS Genetics 2007)
Screens Performed (number of tests): Defects Observed:
Eye: (4)
Vasculature: (1)
- eye absent
(10%, dose:3ng, p53:ng, days: Day: 3)
- eye small size
(10%, dose:3ng, p53:ng, days: Day: 3)
- eye absent
(60%, dose:9ng, p53:ng, days: Day: 3)
- eye small size
(60%, dose:9ng, p53:ng, days: Day: 3)

Images


Figure 1. Tail defects and edema.


Figure 2. Tail defects and edema.